Nicotine replacement therapy is a safe way treatment for smoking cessation. These products work by controlling the addiction to nicotine found in cigarette smoke by delivering controlled amount of nicotine without other harmful substances, this allows patients the control of cravings and the ability to reduce the amount of nicotine they are dependent on with time. NRT products come in various forms (such as nicotine patches and mouth sprays) and can be obtained from the majority of local pharmacies without a prescription.

Champix contains the active ingredient Vareniciline and is only available on prescription. It is recommended as an option for smokers, who have expressed a desire to quit smoking and can tolerate this medication. Vareniciline (Champix) has proven to be a highly effective aid for stopping smoking, with success rates higher than those produced by using NRT.

Bupropion (Zyban) has a mechanism of action that is not clear but this medication is believed to work alteration of noradrenaline and dopamine neurotransmission, however due to the risks associated with this medication, it is less commonly used.

Although all of our content is written and reviewed by healthcare professionals, it should not be substituted for or used as medical advice. If you have any questions about your health, please speak to your doctor.

Authored Dec 22, 2017 by Joseph Issac, MPharm
Reviewed Jun 15, 2021 by Prabjeet Saundh, MPharm