Omeprazole Capsules

From: £12.49

Omeprazole is a generic medication which is commonly used to treat symptoms of acid reflux. It is available as a 20mg capsule and only needs to be taken once daily to provide symptom relief for up to 24 hours.


What is Omeprazole?

Omeprazole belongs to a group of medications called proton pump inhibitors (PPI), which are licensed for the treatment of acid reflux. The branded version of this medication is called Losec, which is manufactured by AstraZeneca.

How does Omeprazole work?

Omeprazole works to control symptoms of acid reflux by reducing acid production in the stomach directly. It does this by blocking an enzyme called a ‘proton pump’, which is involved in the final step of stomach acid formation. Omeprazole works rapidly to control acidity and is effective for up to 24 hours. In some cases it may take up to 4 days to exert its full effect.

How do I take Omeprazole?

Omeprazole 20mg capsules should be taken in the morning at least one hour before food for best absorption. The capsules are enteric coated to ensure they do not break down in the stomach before the medication can produce its desired effect, for this reason Omeprazole capsules should be swallowed whole with water and they should not be crushed or chewed. For those individuals who have difficulty swallowing medication, the omeprazole capsules can be split open and the contents mixed with water or juice before drinking immediately. If there is no improvement in symptoms after 14 days of taking this medication or symptoms are still present after 28 days of treatment, you should see your GP to discuss alternate options.

What are the cautions related to Omeprazole use?

Although Omeprazole is a commonly prescribed medication in the UK, it is still important to check if the medication is suitable for you. Omeprazole should not be used by people suffering with certain conditions or those using certain medications. You should always read the patient information leaflet (PIL) for Omeprazole before taking this medication to ensure it is safe for you to use.

Use of Omeprazole and Antacids
In some patients antacids (Gaviscon, Rennie) may be used in combination with PPIs such as Omeprazole to provide optimal symptom relief. When this combination is used there should be a gap of at least 2 hours between taking the two medications.

What are the side-effects of Omeprazole?

Omeprazole like all medications can be associated with certain side effects although not all patients would experience these.

Common side-effects of Omeprazole include:

  • Abdominal Pain & Flatulence
  • Diarrhoea
  • Constipation
  • Headache
  • Nausea and Vomiting

For more information about the side effects associated with this medication please see the patient information leaflet or contact PostMyMeds.


Where can I find more information on Acid Reflux and Omeprazole?

Please refer to the patient information leaflet (PIL) for Omeprazole for more information on this medication. You can find more information on Acid Reflux on the Conditions category page.

Authored Dec 02, 2015 by Joseph Isaac, MPharm
Reviewed Jun 13, 2019 by Prabjeet Saundh, MPharm

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